Finds a cure for a sickness. Which could be a conspiracy to keep the cure or medicine to treat it a secret from the world population. This is inspired by conspiracy theories of cancer not having a cure yet. That if they one day discovered it. It could be kept a secret for a long time since it is either a billion or trillion dollar industry. Someone the main character knows in the story has the sickness. Maybe cloned humans are experimented on. While this is happening cloned humans can't reproduce and are made to believe they are orphans. This is inner conflict. Give in to the temptation of greed or succumb to guilt. Could be a moral story that speaks volumes on human selfishness. Lord of the rings used both of these themes. If all else fails borrow from themes of stories you admire. Lord of the rings is one example of many. Use your favorite novel for a possible theme and put it in your story. Use works you admire to inspire you. Critics examine theme. It could be worth a try to emulate a work of fiction you admire.
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