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Medieval epidemics would have been more summer things, since the heat would allow diseases such as plague to spread better. But in the winter, I suppose a flu epidemic would have been possible? Probably spread from person to person, and village to village through markets and travelling merchants.
In terms of how the spread would have been limited, a lot of villages would have closed themselves off- a self-quarantine with no one being allowed in or out. There is a famous village which did this during a plague epidemic, but I can't for the life of me remember what it was called...
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"Who is the third who walks always beside you?
When I count, there are only you and I together
But when I look ahead up the white road
There is always another one walking beside you"
-"The Wasteland" by T.S. Elliot
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